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1

Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND

McHutchison, Caroline A, Leighton, Danielle Jane, McIntosh, Andrew, Cleary, Elaine, Warner, Jon, Porteous, Mary, Chandran, Siddharthan, Pal, Suvankar, Abrahams, Sharon

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Année:

2020

Fichier:

PDF, 667 KB

2020

2

A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons

Alastair Wilkins, Siddharthan Chandran, Alastair Compston

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 457 KB

english, 2001

3

Abnormal tau phosphorylation in primary progressive multiple sclerosis

Jane Marian Anderson, Rickie Patani, Richard Reynolds, Richard Nicholas, Alastair Compston, Maria Grazia Spillantini, Siddharthan Chandran

Journal:

Acta Neuropathologica

Année:

2010

Langue:

english

Fichier:

PDF, 631 KB

english, 2010

4

Automated Mechanical Passaging: A Novel and Efficient Method for Human Embryonic Stem Cell Expansion

Alexis Joannides, Christelle Fiore-Hériché, Kristine Westmore, Maeve Caldwell, Alastair Compston, Nicholas Allen, Siddharthan Chandran

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 374 KB

english, 2006

5

Cell-mediated Neuroprotection in P301S Human Tau Transgenic Mice, a Model of Human Tauopathy

Hampton, David W., Webber, Daniel J., Bilican, Bilada, Goedert, Michel, Spillantini, Maria Grazia, Chandran, Siddharthan

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 157 KB

english, 2010

6

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

Barmada, Sami J, Serio, Andrea, Arjun, Arpana, Bilican, Bilada, Daub, Aaron, Ando, D Michael, Tsvetkov, Andrey, Pleiss, Michael, Li, Xingli, Peisach, Daniel, Shaw, Christopher, Chandran, Siddharthan,

Journal:

Nature Chemical Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2014

7

Lateral thinking – Interocular symmetry and asymmetry in neurovascular patterning, in health and disease

Cameron, James R., Megaw, Roly D., Tatham, Andrew J., McGrory, Sarah, MacGillivray, Thomas J., Doubal, Fergus N., Wardlaw, Joanna M., Trucco, Emanuele, Chandran, Siddharthan, Dhillon, Baljean

Journal:

Progress in Retinal and Eye Research

Année:

2017

Langue:

english

Fichier:

PDF, 3.91 MB

english, 2017

8

Elucidating pro-inflammatory cytokine responses following traumatic brain injury in a human stem cell model

Thelin, Eric Peter, Hall, Claire E, Gupta, Kunal, Carpenter, Keri, Chandran, Siddharthan, Hutchinson, Peter John, Patani, Rickie, Helmy, Adel

Journal:

Journal of Neurotrauma

Année:

2017

Langue:

english

Fichier:

PDF, 7.44 MB

english, 2017

9

ALS-specific cognitive and behavior changes associated with advancing disease stage in ALS

Crockford, Christopher, Newton, Judith, Lonergan, Katie, Chiwera, Theresa, Booth, Tom, Chandran, Siddharthan, Colville, Shuna, Heverin, Mark, Mays, Iain, Pal, Suvankar, Pender, Niall, Pinto-Grau, Mart

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 352 KB

english, 2018

10

WED 225 Changing epidemiology of motor neurone disease in scotland

Danielle, Leighton, Siddharthan, Chandran

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Année:

2018

Langue:

english

Fichier:

PDF, 48 KB

english, 2018

11

[IEEE 2019 IEEE International Symposium on Medical Measurements and Applications (MeMeA) - Istanbul, Turkey (2019.6.26-2019.6.28)] 2019 IEEE International Symposium on Medical Measurements and Applications (MeMeA) - Dielectric Measurements of Brain Tissues with Alzheimer’s Disease Pathology in the Microwave Region

Saied, Imran, Bashri, M. S. R., Arslan, Tughrul, Smith, Colin, Chandran, Siddharthan

Année:

2019

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2019

12

Reliability and validity of the brief dimensional apathy scale

Radakovic, Ratko, Gray, Debbie, Dudley, Kaitlin, Mioshi, Eneida, Dick, David, Melchiorre, Giulia, Gordon, Harry, Newton, Judith, Colville, Shuna, Pal, Suvankar, Chandran, Siddharthan, Abrahams, Sharon

Journal:

Archives of Clinical Neuropsychology

Année:

2020

Langue:

english

Fichier:

PDF, 338 KB

english, 2020

13

Household paired design reduces variance and increases power in multi-city gut microbiome study in multiple sclerosis

Zhou, Xiaoyuan, Singh, Sneha, Baumann, Ryan, Barba, Patrick, Landefeld, James, Casaccia, Patrizia, Sand, Ilana Katz, Xia, Zongqi, Weiner, Howard, Chitnis, Tanuja, Chandran, Siddharthan, Connick, Peter

Journal:

Multiple Sclerosis Journal

Année:

2020

Fichier:

PDF, 3.09 MB

2020

14

Regional potential for oligodendrocyte generation in the rodent embryonic spinal cord following exposure to EGF and FGF-2

Siddharthan Chandran, Clive Svendsen, Alastair Compston, Neil Scolding

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 177 KB

english, 1998

15

Differential generation of oligodendrocytes from human and rodent embryonic spinal cord neural precursors

Siddharthan Chandran, Alastair Compston, Eric Jauniaux, Jennifer Gilson, William Blakemore, Clive Svendsen

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 341 KB

english, 2004

16

Multipotent skin-derived precursors: from biology to clinical translation

David P.J. Hunt, Colin Jahoda, Siddharthan Chandran

Journal:

Current Opinion in Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 323 KB

english, 2009

17

Tissue, cell and pathway engineering

Siddharthan Chandran, Gail K Naughton

Journal:

Current Opinion in Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 96 KB

english, 2009

18

Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression

Sabine Golde, Siddharthan Chandran, Guy C. Brown, Alastair Compston

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 582 KB

english, 2002

19

Signaling Pathways Controlling Pluripotency and Early Cell Fate Decisions of Human Induced Pluripotent Stem Cells

Ludovic Vallier, Thomas Touboul, Stephanie Brown, Candy Cho, Bilada Bilican, Morgan Alexander, Jessica Cedervall, Siddharthan Chandran, Lars Ährlund-Richter, Anne Weber, Roger A. Pedersen

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2009

20

Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis

Jane Marian Anderson, Rickie Patani, Richard Reynolds, Richard Nicholas, Alastair Compston, Maria Grazia Spillantini, Siddharthan Chandran

Journal:

Acta Neuropathologica

Année:

2009

Langue:

english

Fichier:

PDF, 514 KB

english, 2009

21

Human Embryonic Stem Cell-Derived Neurons as a Tool for Studying Neuroprotection and Neurodegeneration

Giles E. Hardingham, Rickie Patani, Paul Baxter, David J. Wyllie, Siddharthan Chandran

Journal:

Molecular Neurobiology

Année:

2010

Langue:

english

Fichier:

PDF, 180 KB

english, 2010

22

Minimally manipulated oligodendrocyte precursor cells retain exclusive commitment to the oligodendrocyte lineage following transplantation into intact and injured hippocampus

Daniel J. Webber, Alastair Compston, Siddharthan Chandran

Journal:

European Journal of Neuroscience

Année:

2007

Langue:

english

Fichier:

PDF, 659 KB

english, 2007

23

Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?

Sophie R. Thomson, Thomas M. Wishart, Rickie Patani, Siddharthan Chandran, Thomas H. Gillingwater

Journal:

Journal of Anatomy

Année:

2012

Langue:

english

Fichier:

PDF, 6.98 MB

english, 2012

24

Embryonic Stem Cell-Derived Neural Progenitors Display Temporal Restriction to Neural Patterning

Isabelle A. Bouhon, Alexis Joannides, Hidemasa Kato, Siddharthan Chandran, Nicholas D. Allen

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 521 KB

english, 2006

25

Robust, Persistent Transgene Expression in Human Embryonic Stem Cells Is Achieved with AAVS1-Targeted Integration

Joseph R. Smith, Sean Maguire, Lesley A. Davis, Morgan Alexander, Fentang Yang, Siddharthan Chandran, Charles ffrench-Constant, Roger A. Pedersen

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2008

26

A Highly Enriched Niche of Precursor Cells with Neuronal and Glial Potential Within the Hair Follicle Dermal Papilla of Adult Skin

David P.J. Hunt, Paul N. Morris, Jane Sterling, Jane A. Anderson, Alexis Joannides, Colin Jahoda, Alastair Compston, Siddharthan Chandran

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2008

27

Using human pluripotent stem cells to study post-transcriptional mechanisms of neurodegenerative diseases

Rickie Patani, Christopher R. Sibley, Siddharthan Chandran, Jernej Ule

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 562 KB

english, 2012

28

An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss

David W. Hampton, Jane Anderson, Gareth Pryce, Karen-Amanda Irvine, Gavin Giovannoni, James W. Fawcett, Alastair Compston, Robin J.M. Franklin, David Baker, Siddharthan Chandran

Journal:

Journal of Neuroimmunology

Année:

2008

Langue:

english

Fichier:

PDF, 4.09 MB

english, 2008

29

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

Rickie Patani, Patrick A. Lewis, Daniah Trabzuni, Clare A. Puddifoot, David J. A. Wyllie, Robert Walker, Colin Smith, Giles E. Hardingham, Michael Weale, John Hardy, Siddharthan Chandran, Mina Ryten

Journal:

Journal of Neurochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 974 KB

english, 2012

30

Focal Immune-Mediated White Matter Demyelination Reveals an Age-Associated Increase in Axonal Vulnerability and Decreased Remyelination Efficiency

David W. Hampton, Neill Innes, Doron Merkler, Chao Zhao, Robin J.M. Franklin, Siddharthan Chandran

Journal:

The American Journal of Pathology

Année:

2012

Langue:

english

Fichier:

PDF, 3.78 MB

english, 2012

31

What wires together dies together: Verbs, actions and neurodegeneration in motor neuron disease

Thomas H. Bak, Siddharthan Chandran

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 383 KB

english, 2012

32

Efficient generation of neural precursors from adult human skin: astrocytes promote neurogenesis from skin-derived stem cells

Alexis Joannides, Phil Gaughwin, Christof Schwiening, Henry Majed, Jane Sterling, Alastair Compston, Siddharthan Chandran

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 271 KB

english, 2004

33

Neuroprotective Effect of Oligodendrocyte Precursor Cell Transplantation in a Long-Term Model of Periventricular Leukomalacia

Daniel J. Webber, Marka van Blitterswijk, Siddharthan Chandran

Journal:

The American Journal of Pathology

Année:

2009

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2009

34

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA

Tomohiro Yamazaki, Shi Chen, Yong Yu, Biao Yan, Tyler C. Haertlein, Monica A. Carrasco, Juan C. Tapia, Bo Zhai, Rita Das, Melanie Lalancette-Hebert, Aarti Sharma, Siddharthan Chandran, Gareth Sullivan

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2012

35

Neural stem cells as a potential source of oligodendrocytes for myelin repair

Siddharthan Chandran, Alastair Compston

Journal:

Journal of the Neurological Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 73 KB

english, 2005

36

NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons

Gupta, Kunal, Hardingham, Giles E., Chandran, Siddharthan

Journal:

Neuroscience Letters

Année:

2013

Langue:

english

Fichier:

PDF, 452 KB

english, 2013

37

Management of sialorrhoea in motor neuron disease: A survey of current UK practice

Hobson, Esther V., McGeachan, Alexander, Al-Chalabi, Ammar, Chandran, Siddharthan, Crawley, Francesca, Dick, David, Donaghy, Colette, Ealing, John, Ellis, Cathy M., Gorrie, George, Hanemann, C. Oliver

Journal:

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Année:

2013

Langue:

english

Fichier:

PDF, 407 KB

english, 2013

38

Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis

Hampton, David W, Serio, Andrea, Pryce, Gareth, Al-Izki, Sarah, Franklin, Robin JM, Giovannoni, Gavin, Baker, David, Chandran, Siddharthan

Journal:

Acta Neuropathologica Communications

Année:

2013

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2013

39

Thrombotic Microangiopathy Associated with Interferon Beta

Hunt, David, Kavanagh, David, Drummond, Iain, Weller, Belinda, Bellamy, Chris, Overell, James, Evans, Stephen, Jackson, Andrew, Chandran, Siddharthan

Journal:

New England Journal of Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 398 KB

english, 2014

40

High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology

Stacpoole, Sybil R.L., Spitzer, Sonia, Bilican, Bilada, Compston, Alastair, Karadottir, Ragnhildur, Chandran, Siddharthan, Franklin, Robin J.M.

Journal:

Stem Cell Reports

Année:

2013

Langue:

english

Fichier:

PDF, 6.99 MB

english, 2013

41

Human stem cell-derived neurones as a model to study tau function and dysfunction

Iovino, Mariangela, Patani, Rickie, Chandran, Siddharthan, Spillantini, Maria Grazia

Journal:

Alzheimer's & Dementia

Année:

2011

Langue:

english

Fichier:

PDF, 47 KB

english, 2011

42

Harveian Lecures ON SYPHILITIC DISEASES OF THE EYE AND ITS APPENDAGES.

Foley, Peter L., Vesterinen, Hanna M., Laird, Barry J., Sena, Emily S., Colvin, Lesley A., Chandran, Siddharthan, MacLeod, Malcolm R., Fallon, Marie T.

Journal:

Année:

1897

Langue:

english

Fichier:

PDF, 913 KB

english, 1897

43

Prevalence and natural history of pain in adults with multiple sclerosis: Systematic review and meta-analysis

Foley, Peter L., Vesterinen, Hanna M., Laird, Barry J., Sena, Emily S., Colvin, Lesley A., Chandran, Siddharthan, MacLeod, Malcolm R., Fallon, Marie T.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 916 KB

english, 2013

44

Mesenchymal stromal cell transplantation modulates neuroinflammatory milieu in amyotrophic lateral sclerosis

Connick, Peter, Chandran, Siddharthan

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 90 KB

english, 2014

45

Postnatal Astrocytes Promote Neural Induction from Adult Human Bone Marrow–Derived Stem Cells

Joannides, Alexis, Gaughwin, Phil, Scott, Mike, Watt, Suzanne, Compston, Alastair, Chandran, Siddharthan

Journal:

Journal of Hematotherapy & Stem Cell Research

Année:

2003

Langue:

english

Fichier:

PDF, 641 KB

english, 2003

46

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones

James, Owain T., Livesey, Matthew R., Qiu, Jing, Dando, Owen, Bilican, Bilada, Haghi, Ghazal, Rajan, Rinku, Burr, Karen, Hardingham, Giles E., Chandran, Siddharthan, Kind, Peter C., Wyllie, David J. A

Journal:

The Journal of Physiology

Année:

2014

Langue:

english

Fichier:

PDF, 853 KB

english, 2014

47

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration

Gupta, Kunal, Chandran, Siddharthan, Hardingham, Giles E.

Journal:

British Journal of Clinical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 953 KB

english, 2013

48

Origins of Gliogenic Stem Cell Populations Within Adult Skin and Bone Marrow

Hunt, David P., Sajic, Marija, Phillips, Helen, Henderson, Deborah, Compston, Alastair, Smith, Kenneth, Chandran, Siddharthan

Journal:

Stem Cells and Development

Année:

2010

Langue:

english

Fichier:

PDF, 686 KB

english, 2010

49

Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development

Ruzov, Alexey, Tsenkina, Yanina, Serio, Andrea, Dudnakova, Tatiana, Fletcher, Judy, Bai, Yu, Chebotareva, Tatiana, Pells, Steve, Hannoun, Zara, Sullivan, Gareth, Chandran, Siddharthan, Hay, David C, B

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2011

50

Unpicking neurodegeneration in a dish with human pluripotent stem cells

Bilican, Bilada, Serio, Andrea, Shaw, Christopher E, Maniatis, Tom, Chandran, Siddharthan

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 84 KB

english, 2013